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In distinguishing a Spitz's nevus from melanoma, it is important to realize that some pagetoid spread of melanocytes is acceptable for the diagnosis of a Spitz's nevus as long as the other features of the lesion favor a benign melanocytic proliferation

In order to avoid hypoglycemia in patients on insulin a reduction in insulin dose may be considered, particularly in patients with good glycemic control

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Thus, further studies should carefully analyze whether decreased GSH level increase cancer mortality in humans

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